1/10/2024 0 Comments Caprine eyes![]() Prevention Of Postoperative Elevated IOP Associated With Laser Surgery Following laser iridoplasty, one drop of Isopto ® Carpine 1% should be administered four times daily until an iridotomy can be performed. If laser iridoplasty or iridomy is used to break the attack, one drop of Isopto ® Carpine 4% should be administered prior to the procedure. For initial management of acute angle-closure glaucoma, one drop of Isopto ® Carpine 1% or 2% may be applied topically in the eye(s) up to three times over a 30-minute period. Prior to Isopto ® Carpine use, treatment with secretory suppressants and hyperosmotic agents may be needed to lower IOP below 50 mmHg and relieve iris ischemia. Management Of Acute Angle-Closure Glaucoma ![]() To limit systemic exposure to pilocarpine, patients may be instructed to perform punctal occlusion for 2 minutes after instillation of Isopto ® Carpine ophthalmic solution. The frequency of instillation and concentration of Isopto ® Carpine are determined by the severity of the elevated intraocular pressure and miotic response of the patient. Pilocarpine-naïve patients should be started on the 1% concentration as higher concentrations are often not tolerated initially. One drop of Isopto ® Carpine 1%, 2%, or 4% should be applied topically in the eye(s) up to four times daily. Isopto ® Carpine is indicated for the: Reduction Of Elevated Intraocular Pressure (IOP) In Patients With Open-Angle GlaucomaOr Ocular Hypertension Management Of Acute Angle-Closure Glaucoma Prevention Of Postoperative Elevated IOP Associated With Laser Surgery Induction Of Miosis DOSAGE AND ADMINISTRATION Reduction Of Elevated IOP In Patients With Open-Angle Glaucoma Or Ocular Hypertension Isopto® Carpine has a pH of 3.5 to 5.5 and an osmolality of 290 to 350 mOsm/kg (1% and 2% products) and 550 to 600 mOsm/kg (4% product). Inactives: hypromellose 2910, boric acid, sodium citrate, sodium chloride (present in 1% only) hydrochloric acid and/or sodium hydroxide (to adjust pH) purified water. Preservative: benzalkonium chloride 0.01%. Molecular Formula: C 11H 16N 2O 2 Įach mL of Isopto® Carpine (pilocarpine hydrochloride ophthalmic solution) contains: Active: pilocarpine hydrochloride 1% (10 mg/mL), 2% (20 mg/mL), or 4% (40 mg/mL). The active ingredient is represented by the chemical structure:Įstablished name: pilocarpine hydrochlorideĬhemical name: 2(3 H)-furanone, 3-ethyldihydro-4- monohydrochloride, (3S-cis). Isopto® Carpine (pilocarpine hydrochloride ophthalmic solution) is a cholinergic agonist prepared as a sterile topical ophthalmic solution. Tell your doctor if you have unlikely but serious side effects of Isopto Carpine including:
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